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the hormone reset duo

dim elite cdg + metaburn

Title

Clear the estrogen your body is finished with. Work with the hunger signal instead of against it.

Metaburn: 500 mg Metabolaid® works on appetite signalling and AMPK, your cells' fuel gauge

DIM Elite CDG: 3C and DIM steer estrogen down its protective 2-OH pathway, and a full gram of Calcium D-Glucarate protects the exit

Together: a pathway that finishes, and a hunger signal that quiets down.

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Description

Two formulas for the part of weight that isn't about willpower. 

 

DIM Elite CDG supports the whole estrogen pathway... not just where estrogen is made, but where it's metabolized and where it leaves.

 

Metaburn works on the hormones that set your hunger and on AMPK, the enzyme that decides whether your cells burn stored energy or bank more of it. Estrogen handling and appetite signalling, supported at the same time. No stimulants in either bottle.

How to Use

DIM Elite CDG: 3 capsules daily with a meal. 

 

Metaburn: 2 capsules before your largest meal. Full schedule in the protocol table below.

finish the pathway

DIM Elite CDG supports estrogen where it's actually processed, not just where it's made. I3C and DIM work on the fork in the road... favouring the protective 2-OH metabolite over the harsher 4-OH and 16α-OH routes. Then a full gram of Calcium D-Glucarate protects the liver's packaging so what got cleared actually leaves. Plus 700 mg of Inositol for insulin and ovarian signalling, and Vitamin E for antioxidant cover while all of it happens.

change the signal

Metaburn works on the part of weight management that discipline doesn't reach: the hormones that set your hunger. Metabolaid® polyphenols support AMPK… your cells' fuel gauge… and have been studied for their effect on satiety signalling, including GLP-1 and ghrelin. The green coffee bean extract is decaffeinated on purpose. The polyphenols are the point, not the caffeine.

QUALITY GUARANTEED
THIRD PARTY-TESTED
NO UNNECESSARY FILLERS
100% GLUTEN-FREE
NON-GMO
QUALITY GUARANTEED
THIRD PARTY-TESTED
NO UNNECESSARY FILLERS
100% GLUTEN-FREE
NON-GMO

Two formulas that work 
better together

Each one is backed by its own research and works on its own. Together they cover the two halves of a complaint that almost never has one cause: how well your body clears the estrogen it's finished with, and how loud your hunger signal is while you're trying to do something about it.

Your liver packages used estrogen for disposal and hands it to the gut. An enzyme there... beta-glucuronidase... can unwrap that package and send the estrogen straight back into circulation. Calcium D-Glucarate inhibits that enzyme, so what your liver cleared actually leaves. DIM Elite CDG uses a full gram per serving. Most DIM products contain none at all.
Estrogen doesn't break down one way. Your liver converts it into metabolites, and it matters enormously which ones... the 2-OH route is the gentle one, while 4-OH and 16α-OH keep cells stimulated. 200 mg of I3C and 100 mg of DIM work on that fork in the road. The DIM is dosed directly, so you're not relying on digestion to make it.
700 mg of Inositol supports insulin signalling and ovarian function — the upstream conditions that shape how much estrogen you're making in the first place, and the reason this formula gets used for cycle regularity and premenstrual mood. 33.5 mg of Vitamin E, as d-alpha tocopheryl succinate, gives cell membranes antioxidant cover while all of it is happening.
Three capsules daily with a meal, or as directed by your healthcare practitioner. Each bottle holds 90 capsules... a full 30-day supply. Estrogen clearance is a pathway, not a switch, so most people do best giving it a consistent two to three months. Do not use if pregnant or nursing.
The Remodeler
GLP-1 (glucagon-like peptide-1) is a powerful hormone naturally produced in your gut that regulates appetite, promotes feelings of fullness, and supports healthy metabolic function. Small studies show that certain natural compounds like berberine, curcumin, and specific plant extracts may help boost GLP-1 levels naturally.
Here's what most people miss: Your gut produces GLP-1. Specialized L-cells in your intestinal lining are responsible for secreting this metabolic hormone. When your gut lining is damaged and microbiome imbalanced, GLP-1 production suffers. By restoring gut health first with Remodeler and Align, you create the optimal foundation for natural GLP-1 support.
Research shows that natural GLP-1 support may help with appetite control, slower gastric emptying (keeping you satisfied longer), improved insulin sensitivity, and optimized metabolic efficiency. Combined with a healthy gut environment, this creates the ideal conditions for sustainable, long-term weight management and metabolic health.
Take 2 capsules daily before your first meal
Letter From the Founder

i'm dr. cassie smith, 

founder of modern endocrine.

With dual board certifications in endocrinology, diabetes, metabolism, and internal medicine, Dr. Smith brings a wealth of expertise and experience to her practice.

 

Her journey in medicine began at the University of Missouri Kansas City, where she completed both her undergraduate and medical degrees with distinction.

 

During her residency, Dr. Smith’s exceptional dedication and leadership were recognized when she was awarded Chief Resident of her class.

Featured In:

Why These Two Work Better Together
The Synergistic Effect

What you can expect

Individual results may vary. Research suggests gut healing typically requires 6 months to a year for significant improvements.

Week 1-2

Foundation Phase

  • Both formulas at full dose, beginning to establish
  • Appetite signalling is usually the first thing people notice a change in
  • B-vitamin support for everyday energy begins building
Week 3-8

Regulation Phase

  • The full Metaburn loading protocol... this is the stretch that does the work on hunger-hormone regulation
  • Methylation support builds with consistent daily use
  • Better appetite control through the evening hours
Week 9+

Maintenance Phase

  • Metaburn steps down to the maintenance dose, holding the regulation in place
  • Ongoing support for healthy body composition and metabolic function
  • Continued support for energy, mood and mental clarity

1000+ SATISFIED PATIENTS

Real results from real people

"After just 3 weeks on this bundle, my bloating is gone and I finally feel comfortable in my own body. The weight loss is a bonus!" 

~ Sarah M. 

"As a healthcare provider, I'm impressed with the quality and synergy of these products. I recommend them to my patients." 

~ Dr. Jennifer K.

"I've tried everything for my gut issues. This is the first system that actually worked. My digestion, energy, and weight are all better." 

~ Michael R.

YOUR HORMONES ARE HANDLED. THE WEIGHT ISN'T.

Body fat makes estrogen, and estrogen influences where fat is stored. It’s a loop... not a discipline problem.

 

These formulas support estrogen metabolism and hunger signals, so your effort can finally start showing.

Frequently asked
questions

Do I need both, or can I start with one? 

Each works on its own. DIM Elite CDG supports estrogen metabolism and clearance; Metaburn works on appetite signalling and AMPK. They're paired because the weight that settles on hips and midsection usually has something happening on both sides. If you're starting with one, start with the one that matches your bigger complaint: heavy cycles, bloat and hormonal skin, or hunger that doesn't quit in the evenings.

Can I take this with hormone replacement therapy? 

This is arguably where it matters most. HRT gives your body estrogen; it doesn't change how well you process it. DIM Elite CDG supports the metabolism and clearance side, which is why so many practitioners pair the two. Metaburn contains no hormones at all. Talk to whoever manages your therapy before you add either one.

 Is Metaburn like a GLP-1 medication?

No... and it's important to be clear about that. Metaburn is a dietary supplement. It contains no semaglutide, tirzepatide, or any other medication, and it is not a substitute for one. The polyphenols in Metabolaid® have been studied for supporting your body's own satiety signalling, including GLP-1, which your gut produces naturally. Different mechanism, different category, different magnitude. If you're on or considering a GLP-1 medication, talk to your prescriber before adding anything.

Will either of these make me jittery?

No. There are no stimulants in either bottle. Metaburn's green coffee bean extract is decaffeinated on purpose... we wanted the chlorogenic acids, not the caffeine. DIM Elite CDG contains nothing stimulating either.

My urine turned a strange colour. Is something wrong?

No... that's DIM, and it's harmless. DIM can tint urine an orange or amber colour, sometimes within the first few days. It's cosmetic, it's well documented, and it isn't a sign that anything is wrong or that you're taking too much.

Is this only for women?

No. Men over 40 often deal with rising aromatization... testosterone converting to estrogen... and DIM and I3C support healthy estrogen metabolism in men too, which helps protect free and active testosterone. Metaburn isn't gender-specific at all. If the visitor came in from a men's-health path, Dude DIM may be the better fit for the hormone half.

Can I take them at the same time? 

You can, but the schedule below works better. DIM Elite CDG goes with a meal... three capsules, once a day, and breakfast is the easiest habit to keep. Metaburn is timed to meals too, because appetite signalling support is most useful just before you eat.

How long before I notice anything? 

Appetite changes are usually first, often within the first few weeks. Bloat and mood tend to follow in the first two to three weeks. Cycle symptoms and skin generally take 30 to 60 days. 

Is this safe for long-term use?

Both are designed for ongoing daily use, and the maintenance phase is where hunger-hormone regulation is held in place... the part that matters for keeping results. Talk to your practitioner about what's right for you.

Can I take these with other Modern Endocrine products? 

Yes. This protocol pairs particularly well with Insulin Impact... Metaburn works on appetite signalling and AMPK, Insulin Impact works on the glucose side, and most people dealing with stubborn weight have something happening on both.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Consult your healthcare provider before starting any new supplement regimen, especially if you are pregnant, nursing, taking medication, or have a medical condition.

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How to use the 
hormone reset protocol

Morning

Before Dinner

Before Lunch

Mighty Methyl Folate

2 Capsules

Title
Title

Metaburn

Title

2 Capsules

start the hormone reset duo 

Stop fighting a loop you can't out-discipline. 

Start supporting both sides of it.