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The Replenisher - 90 Caps Modern Endocrine
The Replenisher - 90 Caps Modern Endocrine

Replenisher - 90 Caps

$48.00

Safe & Tested Ingredients

Dr. Formulated

Optimized For You

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Clinical Applications

  • Helps Maintain Normal Gastrointestinal Balance
  • Provides Concentrated Immunoglobulins to Enhance Mucosal Immunity
  • Supports Digestion and Micronutrient Absorption
  • Maintains GI Barrier Health and Integrity

SIBO is a condition that occurs when there is an overabundance of commensal bacteria from the colon present in the small intestine. The health of the small intestines relies on balanced microbiota, and probiotics and immunoglobulins can contribute to that balance by having a positive influence on the intestinal environment, including pH, organism diversity, and immune signaling.

Probiotics have been extensively studied and are characterized as having broad GI and immune benefits. Probiotics are live organisms and must be shelf stable through the expiration date, so they can be precisely delivered to the intestinal tract to have maximum benefit. Bacillus spores remain dormant in harsh environments until they reach more favorable environments like the human gastrointestinal tract. The combination of specific strains, particularly Bacillus coagulans, Bacillus clausii, and Bacillus subtilis, relieve symptoms for common GI complaints and reinforce healthy gut function.

In the search for innovative ways to improve microbiome diversity, we have combined our blend of spore-forming probiotics alongside immunoglobulins uniquely shown to bind to bacteria and toxins, driving immune response. Replenisher helps to maintain a healthy intestinal immune system by binding a broad range of microbes and toxins within the gut lumen.

Bacillus coagulans

Bacillus coagulans has been shown to increase the commensal GI microbiota. It has been shown to relieve GI discomfort and improve stool consistency. B. coagulans also significantly improved bowel movements in healthy adults with occasional constipation, as well as decreased abdominal discomfort.

Bacillus clausii

B. clausii is commonly used as a probiotic to promote balance in the microbiome and has showed promising results in individuals with SIBO. B. clausii has demonstrated significant effectiveness in adults with acute diarrhea. B. clausii has also shown to significantly reduce duration of occasional diarrhea and decreased stool frequency in children

Bacillus subtilis

Bacillus subtilis has been shown to relieve GI distress in patients.

Serum-derived bovine immunoglobulins

Probiotics are a natural choice for supporting beneficial bacteria in the gut, but supplementation to eliminate unwanted microbes should also be considered. Within the gut barrier, researchers found that the binding capabilities of immunoglobulins have a positive effect on gut barrier function in vitro. Broad-spectrum binding capabilities demonstrate the positive influence of serum-derived bovine immunoglobulins. This binding and elimination decreases microbe and toxin encounters by the immune system and resets immune tolerance.

3 capsules per day or as recommended by your health care professional.

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Replenisher - 90 Caps

$48.00 USD

Clinical Grade Products

Formulated using clinically studied ingredients and produced under strict quality standards. Each of our products undergoes thorough review to guarantee safety, purity, and potency.

Cassie Smith, MD Approved

Cassie Smith, MD is dual board-certified in endocrinology, diabetes, metabolism, and internal medicine. She’s a certified health care professional who understands the power of high quality vitamin and supplement formulas. She has approved every selected ingredient to support your long term wellness.

Why Our Supplements Work

Expert-Selected

Expertly Curated

Every product is hand-selected by Dr. Cassie Smith and our team of medical professionals, rooted in science, not trends.

Compassionate Service

Compassionate Care

We prioritize your comfort, well-being, and long-term success with supplements designed to support real healing, not just symptom relief.

Holistic Approach

Whole-Body Wellness

We take a functional, holistic approach—pairing high-quality supplements with lifestyle guidance, nutrition support, and stress management.

Frequently Asked Questions

How should I store my supplements?

Most supplements should be kept in a cool, dry place away from direct sunlight. 

Are your supplements third-party tested?

Our manufacturer maintains a legacy of good manufacturing practices, instated long before cGMPs became compliance requirements. They stay up-to-date on industry research and testing methods,  and fine-tune their manufacturing  practices accordingly. They own and operate a cGMP, FDA-audited manufacturing and distribution facility here in the United States. The facility is equipped with high-performance HVAC and desiccant control that maintains ideal manufacturing conditions. Their staff are highly trained personnel who share a passion for efficacy. Because they control the entire production process—from formulation, raw material sourcing, and manufacturing, to laboratory testing of incoming materials and finished products, to bottling and labeling—they are free to be perfectionists. Their manufacturing facility is strictly controlled by rigorous standards that  meet cGMPs, and it routinely passes FDA and third-party audits. Extensive testing  on every lot they manufacture means you can trust the consistent purity, strength, identity and composition of each and every product formula.

Do you ship internationally?

Currently we only ship inside the United States.

What is your return policy? 

We accept returns on unopened products within 30 days of purchase. Please see our full return policy here

When are orders shipped?

Orders are typically shipping out the next business day.  Weather events or holidays can affect processing time. Customers will receive an email with tracking upon their order processing.

Still need help? 

Please visit or contact page here

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