4.7 Stars (116 Reviews)

Pylori Plus

Name: Pylori Plus
Brand: Modern Endocrine
SKU: 37ENDRQA0E
Price: 59.0 USD
Availability: InStock

Pylori Plus is a targeted gastrointestinal formula designed to promote healthy microbial balance, soothe the stomach lining, and restore lasting digestive comfort… without disrupting the rest of your gut.

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Ingredients

Mastic Gum Extract (250mg)
Berberine Hydrochloride Hydrate (150mg)
Bismuth Citrate USP (125mg)
Zinc Carnosine (37.5mg)
Zinc (as Zinc Carnosine) (8.5mg - 77% DV)

How to Use

Take 1 capsule two times per day, or as recommended by your healthcare professional.

why we made this

The CDC estimates that approximately two-thirds of the world’s population has stomach microbial balance concerns. While many never experience symptoms, others suffer silently with persistent stomach discomfort, burning, bloating, and nausea for years. Most over-the-counter solutions just mask symptoms. Pylori Plus takes a different approach… four targeted ingredients that work together to restore healthy microbial balance, soothe the stomach lining, and support your body’s natural defense systems.

Four Targeted Ingredients.
One Comprehensive Formula.
Complete Stomach Defense.

Most stomach supplements address only one piece of the puzzle. Pylori Plus combines mastic gum, berberine, bismuth citrate, and zinc carnosine to tackle microbial imbalance, protect the stomach lining, and promote lasting GI comfort… all in one daily formula.

Mastic Gum Extract - 250mg

A resinous extract from the mastic tree (Pistacia lentiscus), used for centuries in Mediterranean medicine to support stomach health. Promotes healthy microbial balance and helps soothe the gastric lining.

Berberine Hydrochloride - 150mg

A well-researched botanical extract with a long history in Ayurvedic and Chinese medicine. Promotes healthy microbial balance in the GI tract and supports normal inflammatory balance throughout the body.

Bismuth Citrate USP - 125mg

A naturally occurring mineral frequently used to soothe the gastric and mucosal linings. Bismuth citrate promotes microbial balance and provides a protective coating that helps shield the stomach lining.

Zinc Carnosine - 37.5mg

Approved in Japan since 1994 for stomach health support. Zinc’s health-promoting effects are enhanced significantly when combined with the essential nutrient carnosine, supporting stomach lining integrity and repair.

QUALITY GUARANTEED

THIRD PARTY-TESTED

NO UNNECESSARY FILLERS

100% GLUTEN-FREE

NON-GMO

QUALITY GUARANTEED

THIRD PARTY-TESTED

NO UNNECESSARY FILLERS

100% GLUTEN-FREE

NON-GMO

only natural ingredients

Always free of artificial colors & preservatives, fillers, gluten, GMOs, and synthetic additives.

Mastic Gum Extract (Pistacia lentiscus)

Mastic gum is a resinous product obtained from the stem and leaves of the mastic tree, an evergreen shrub native to the Mediterranean Basin. It has been used historically to support stomach health and promote healthy microbial balance. Modern research confirms its role in soothing the gastric lining and maintaining a comfortable digestive environment. At 250mg per capsule, Pylori Plus delivers a clinically relevant dose.

Berberine Hydrochloride Hydrate

Berberine is a botanical alkaloid found in the roots and barks of plants including Oregon grape root, barberry, and goldenseal. With a long history in both Ayurvedic and Chinese medicine, berberine has been shown to promote healthy microbial balance in the GI tract and maintain normal inflammatory balance throughout the body. It also supports healthy blood sugar levels and helps restore gut motility.

Bismuth Citrate USP

Bismuth citrate is a naturally occurring mineral compound with a long track record of use in gastrointestinal health. It soothes the gastric and mucosal linings by forming a protective coating over the stomach wall, shielding it from acid and irritation. Bismuth also promotes healthy microbial balance, making it a dual-action ingredient for stomach comfort and defense.

Zinc Carnosine/h3>
Zinc carnosine is a chelated compound that has been approved in Japan since 1994 for its role in stomach health. Unlike standard zinc supplements, the combination of zinc with the amino acid carnosine allows it to adhere to the stomach lining where it provides targeted support. Research shows zinc carnosine supports mucosal integrity, promotes tissue repair, and helps maintain a healthy stomach environment. At 37.5mg per capsule, plus an additional 8.5mg of elemental zinc (77% DV), Pylori Plus ensures comprehensive zinc support.

Pylori Plus has helped thousands of patients restore stomach comfort and healthy microbial balance.

Don’t just take our word for it. See for yourself what our patients experience within 60-90 days of taking Pylori Plus.

1000+ SATISFIED PATIENTS

join the stomach health revolution

Hear from patients everywhere who are finally finding relief from persistent stomach discomfort.

MY STOMACH FINALLY FEELS NORMAL

I’d been dealing with constant stomach burning and discomfort for over a year. Antacids helped temporarily but never fixed the problem. Within three weeks of Pylori Plus, the burning stopped. By month two, I could eat meals without worrying about the aftermath. This is the real solution I’d been looking for.

Angela T.

LIFE-CHANGING RELIEF

My doctor found I had microbial balance concerns and I wanted a natural approach alongside my treatment plan. Pylori Plus made a noticeable difference within the first month. The bloating and nausea I’d lived with for years are gone. I feel like I have my life back.

David P.

FINALLY, SOMETHING THAT WORKS

I’ve tried every over-the-counter stomach product out there. Nothing worked long-term until Pylori Plus. The combination of mastic gum and zinc carnosine is clearly doing something different. My GI doc was impressed with my improvement at my follow-up. Highly recommend.

Lisa M.

Letter From the Founder

i'm dr. cassie smith,

founder of the pylori plus

Stomach discomfort is one of the most common complaints I hear in my practice... and one of the most undertreated. Patients come in with years of burning, bloating, and nausea, having cycled through antacids and acid blockers that never address the root cause. The problem isn’t too much acid. It’s usually a microbial imbalance that’s damaging the stomach lining.

The CDC estimates two-thirds of the world’s population has stomach microbial balance concerns. That’s staggering… and it told me we needed a better solution than symptom suppression.

I formulated Pylori Plus with four ingredients that work synergistically: mastic gum to promote microbial balance, berberine for broad antimicrobial support, bismuth citrate to coat and protect the stomach wall, and zinc carnosine to repair and strengthen the lining. Together, they address the cause AND the damage.

Two capsules a day. Real stomach relief. Real healing.

Dr. Cassie Smith

FAQs for Pylori Plus

What is Pylori Plus?

Pylori Plus is a targeted gastrointestinal health supplement formulated to promote healthy microbial balance in the stomach and GI tract, soothe the stomach lining, and support lasting digestive comfort. It combines mastic gum extract, berberine hydrochloride, bismuth citrate, and zinc carnosine… four ingredients with complementary mechanisms of action.

Who should take Pylori Plus?

Pylori Plus is ideal for anyone experiencing persistent stomach discomfort, burning, bloating, or nausea related to microbial imbalance. It’s especially helpful for those seeking a natural approach to stomach health, people who’ve tried antacids without lasting relief, and anyone looking to support healthy microbial balance in the GI tract.

How is Pylori Plus different from antacids?

Antacids and acid blockers suppress stomach acid to temporarily relieve symptoms, but they don’t address the underlying microbial imbalance that’s often causing the discomfort. Pylori Plus targets the root cause… promoting healthy microbial balance while simultaneously soothing and protecting the stomach lining with zinc carnosine and bismuth citrate.

How do I take Pylori Plus?

Take 1 capsule two times per day with or without food, or as recommended by your healthcare professional. For best results, take consistently for 60-90 days.

When will I see results?

Many people notice reduced stomach discomfort within the first 1-2 weeks. Significant improvement in overall GI comfort and microbial balance typically appears within 30-60 days of consistent use.

Can I take this with other supplements or medications?

Pylori Plus works well alongside most GI health protocols. However, because it contains berberine and bismuth, consult your healthcare provider if you’re on prescription medications, especially blood sugar medications or antibiotics. Bismuth may temporarily darken stools — this is normal and harmless.

Is this safe long-term?

Pylori Plus is formulated with well-researched, naturally derived ingredients. For extended use beyond 60-90 days, consult your healthcare practitioner to determine the best ongoing protocol for your individual needs.

What does bismuth citrate do?

Bismuth citrate is a naturally occurring mineral that serves two purposes: it forms a protective coating over the stomach and mucosal linings (shielding them from acid and irritation), and it promotes healthy microbial balance in the GI tract. It’s one of the most well-established ingredients in stomach health.

Why zinc carnosine instead of regular zinc?

Zinc carnosine is a chelated form of zinc that adheres to the stomach lining, delivering targeted support exactly where it’s needed. Approved in Japan since 1994 for stomach health, the combination of zinc with carnosine enhances zinc’s protective and reparative effects on the mucosal lining far beyond what standard zinc supplements can provide.

Can I take this if I’m pregnant or breastfeeding?

Consult your healthcare provider before starting any new supplement during pregnancy or breastfeeding. The ingredients in Pylori Plus should be reviewed with your practitioner based on your individual health needs.

Still have questions?

Contact our team at hello@modern-endocrine.com

We're here to help!

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Pylori Plus

why we made this